VATI Pediatrics Practice Exam

The most commonly associated complication with cystic fibrosis is indeed constipation. This is primarily due to the thick, sticky secretions produced in the intestines, which can lead to bowel obstruction and difficulty in stool passage. The abnormal mucus in the digestive tract affects the normal function of the intestines, often resulting in a slower transit time and harder stools.

In cystic fibrosis, the pancreas can also be affected, resulting in decreased enzyme production necessary for proper digestion. This can further contribute to gastrointestinal issues, including constipation. Patients may struggle with proper nutrient absorption, additional factors that can lead to constipation.

While dehydration, liver failure, and diabetes are important considerations in the management of cystic fibrosis, they are not as directly linked to the disease’s characteristic symptoms as constipation. Dehydration can occur due to excessive sweating and loss of salt, liver failure can be a long-term complication due to biliary obstruction, and diabetes can develop over time as pancreatic function declines, but constipation is more commonly experienced and recognized in cystic fibrosis patients.